发明名称 COMPOSITION COMPRISING A TRAMADOL MATERIAL AND AN ANTICONVULSANT DRUG
摘要 This invention relates to a pharmaceutical composition comprising a combination of a tramadol material and an anticonvulsant drug and to the pharmacological use of the composition in treating conditions of pain and neurologic or psychiatric disorders. The composition produces a combination product having improved properties, requiring less of each ingredient and producing a synergistic effect.1. tramadol, dose ED50.2. topiramate, dose ED50.
申请公布号 EA006598(B1) 申请公布日期 2006.02.24
申请号 EA20020000183 申请日期 2000.08.09
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 CODD ELLEN, E.;MARTINEZ REBECCA, P.;ROGERS KATHRYN, E.
分类号 A61K45/00;A61K45/06;A61K31/135;A61K31/195;A61K31/215;A61K31/35;A61K31/53;A61P25/04;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/22;A61P25/28 主分类号 A61K45/00
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