INTRA-AORTIC RENAL DRUG DELIVERY CATHETER

摘要

A fluid agent is delivered to the renal system using an abdominal aortic flow isolation assembly. In certain aspects, a tubular member (13) extends within the aorta (31) across the renal ostia, with a radially expandable interior passageway (18) separating aortic blood flow into outer (33) and inner streams. A radially expandable member (14) on the tubular member (13) is located down-stream of an agent delivery port (25) coupled to the outer stream, with an expanded configuration having an outer diameter larger than the tubular member (13) and that inhibits the outer blood flow stream (33) from flowing downstream of the branch vessel (32). One or more fluid agents such as Papaverine, a calcium-channel blocker, Nifedipine, Verapamil, Fenoldapam, or a dopamine DA<sub