| 发明名称 |
Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity |
| 摘要 |
Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of the substituents are provided herein.
|
| 申请公布号 |
US2006040965(A1) |
申请公布日期 |
2006.02.23 |
| 申请号 |
US20050169313 |
申请日期 |
2005.06.29 |
| 申请人 |
AMGEN INC. |
发明人 |
FARTHING CHRISTOPHER N.;FAULDER PAUL;FRENKEL ALEXANDER D.;HARRISON MARTIN J.;JIAO XIANYUN;KAYSER FRANK;KOPECKY DAVID J.;LIU JINQIAN;LIVELY SARAH E.;SHARMA RAJIV;SHUTTLEWORTH STEPHEN J. |
| 分类号 |
A61K31/519;C07D487/02 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
