发明名称 |
Macrocycles useful in the treatment of Alzheimer's disease |
摘要 |
The present invention are macrocycles of the formula (IX): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
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申请公布号 |
US2006040910(A1) |
申请公布日期 |
2006.02.23 |
申请号 |
US20050218879 |
申请日期 |
2005.09.02 |
申请人 |
PULLEY SHON R;BECK JAMES P;TENBRINK RUTH E |
发明人 |
PULLEY SHON R.;BECK JAMES P.;TENBRINK RUTH E. |
分类号 |
A61K31/33;A61K31/395;A61K31/4427;A61P25/28;C07D267/22;C07D273/02;C07D413/12 |
主分类号 |
A61K31/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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