METHODS OF DIAGNOSIS OR DETECTION USING THREE-DIMENSIONAL ANALYSIS

摘要

The invention provides methods of diagnosing or detecting hereditary breast cancer versus non-hereditary breast cancer. In particular, the invention relates to methods of diagnosing or detecting breast cancer cells that have mutant BRCA1 or BRCA2 genes as compared to wild type BRCA1 and BRCA2 genes. The invention also provides methods of detecting cancer using 3D analysis and genetic analysis. In particular, characterizing the telomeric organization of a cell and genetically analyzing the cell for the presence of a translocation, deletion or amplification. In addition, the invention provides methods of simultaneously analyzing protein and nuclear structures of a cell using 3D analysis.