Phosphinate compounds of general formula (I) or pharmaceutically acceptable salts or esters thereof, that are capable of potently inhibiting proteases such as, e.g., metallo proteases or aspartate proteases, especially HIV protease including HIV-1 proteases. A compound of the invention is therefore useful as an active substance in the treatment of HIV related diseases such as AIDS.
申请公布号
WO2005105843(A3)
申请公布日期
2006.02.23
申请号
WO2005DK00296
申请日期
2005.04.29
申请人
ARPIDA A/S;JENSEN, CHRISTIAN, EEG;BONDEBJERG, JON;NAERUM, LARS
发明人
JENSEN, CHRISTIAN, EEG;BONDEBJERG, JON;NAERUM, LARS