发明名称 |
METHODS OF DIAGNOSIS AND TREATMENT OF M. TUBERCULOSIS INFECTION AND REAGENTS THEREFOR |
摘要 |
<p>The present invention provides diagnostic, prognostic and therapeutic reagents for infection of an animal subject such as a human by M. tuberculosis, and conditions associated with such infections, such as, for example, tuberculosis. More particularly, the present invention provides a recombinant protein of M. tuberculosis designated "BSX" (SEQ ID NO: 1) and immunogenic epitopes thereof such as, for example, comprising SEQ ID NOS: 34, 25 and 45, that are useful in antibody-based diagnostic applications. The present invention also provides antibodies against BSX and its immunogenic peptides that are useful for antigen-based diagnostic and prognostic tests, and for therapy and vaccine formulations.</p> |
申请公布号 |
WO2006017912(A1) |
申请公布日期 |
2006.02.23 |
申请号 |
WO2005AU01254 |
申请日期 |
2005.08.19 |
申请人 |
PROTEOME SYSTEMS INTELLECTUAL PROPERTY PTY LTD;MACKINTOSH, JAMES, A;COLE, ROBERT, ALAN |
发明人 |
MACKINTOSH, JAMES, A;COLE, ROBERT, ALAN |
分类号 |
(IPC1-7):C07K14/35;C07K16/12;C07K7/08;C07H21/04;A61K38/16;A61K38/10;A61K39/04;A61P31/06;G01N33/68;G01N33/563;G01N33/53;G01N33/577 |
主分类号 |
(IPC1-7):C07K14/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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