发明名称 Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom
摘要 The present invention provides a rapid, high-yielding process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one from 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one without using a secondary amine as a catalyst, and without using glacial acetic acid as a solvent. The present invention further provides a rapid, high-yielding process for preparing ondansetron from 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one without using alumina as a catalyst.
申请公布号 US2006041004(A1) 申请公布日期 2006.02.23
申请号 US20050204539 申请日期 2005.08.16
申请人 GUTMAN DANIELLA;CYJON ROSA 发明人 GUTMAN DANIELLA;CYJON ROSA
分类号 A61K31/403;C07D209/82 主分类号 A61K31/403
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