发明名称 |
Method for producing steroid crystals, crystals obtained by said method and their use in pharmaceutical formulations. |
摘要 |
The process for making steroid crystals having a predetermined average particle size of from 1 mum to 25 mum and a maximum particle size that does not exceed a predetermined maximum value of 100 mum, includes subjecting a supersaturated solution containing a steroid to a wet milling by wet milling apparatus while crystallizing, in order to obtain a primary particle suspension. Crystals obtained according to this process and pharmaceutical preparations containing them are also described. |
申请公布号 |
ZA200409401(B) |
申请公布日期 |
2006.02.22 |
申请号 |
ZA20040009401 |
申请日期 |
2004.11.22 |
申请人 |
SCHERING AG. |
发明人 |
DETLEF GRAWE;PETER HOESEL;SABINE GLIESING;HAGEN GERECKE;ANNETTE EICHARDT;UWE MUELLER |
分类号 |
A61K31/56;A61K31/567;A61K31/568;A61P43/00;C07J1/00;C07J41/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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