发明名称 Process for preparing hydrohalogen metal complexes of specific particle size
摘要 Production of a granular hydrohalide (A) of a complex (I), comprising a central divalent metal cation and an aminodicarboxylic acid ion and optionally water as ligands, involves spray-drying an aqueous solution of (I) hydrohalide at an air inlet temperature of 300-350[deg]C, an air outlet temperature of 100-140[deg]C and a spray pressure of 3-5 bars. An independent claim is included for granular (I) hydrohalide (A') obtained by the process, having at least 10% of the particles of size more than 50 mu m and at least 10% of the particles of size less than 400 mu m (preferably at least 80% of the particles in the 100-315 mu m range, especially at least 50% of the particles in the 140-250 mu m range). MECHANISM OF ACTION : None given.
申请公布号 EP1627879(A1) 申请公布日期 2006.02.22
申请号 EP20040019858 申请日期 2004.08.20
申请人 VERLA-PHARM ARZNEIMITTELFABRIK APOTHEKER H.J.N EHRLICH GMBH & CO. KG 发明人 HOPF, GUENTER
分类号 C07F3/00;A23K1/16;A61K31/28;C07F19/00 主分类号 C07F3/00
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