发明名称 |
Nucleic acid molecules encoding modified polyketide synthases containing polylinkers and uses thereof |
摘要 |
Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nucleic acid incorporated into the polylinker, the further nucleic acid encoding one or more reductive enzymes; plasmids incorporating such nucleic acids; host cells transfected with such plasmids; methods relating thereto.
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申请公布号 |
US7001747(B1) |
申请公布日期 |
2006.02.21 |
申请号 |
US20010743162 |
申请日期 |
2001.08.24 |
申请人 |
PFIZER, INC. |
发明人 |
KELLENBERGER JOHANNES;LEADLAY PETER FRANCIS;STAUNTON JAMES;STUTZMAN-ENGWALL KIM JONELLE;MCARTHUR HAMISH ALASTAIR IRVINE |
分类号 |
C12N15/09;C12P19/62;C07K19/00;C12N1/21;C12N9/02;C12N9/04;C12N9/10;C12N9/88;C12N15/52;C12P17/06;C12R1/465 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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