Non-natural C-linked carbo-beta-peptides with robust secondary structures

摘要

Nonnatural C-linked carbo-beta-peptides with robust secondary structures, which involves the synthesis of a new class of beta-peptides called C-linked carbo-beta-peptides. The compounds are favorably disposed for the formation of stable helical structures and are useful as biologically active carbo-beta-peptides. The new class of beta-peptides have the following formula