METHOD AND INSTRUMENT FOR LOW TEMPERATURE MICROWAVE ASSISTEDORGANIC CHEMICAL SYNTHESIS

摘要

An instrument and associated method are disclosed for performing microwave assisted organic chemical synthesis at low temperatures. The instrument includes a reaction vessel formed of a microwave transparent material that defines an interior reaction chamber for carrying out microwave assisted reactions in the chambe r, a cooling jacket immediately surrounding the reaction vessel for cooling the vessel and the vessel contents during the application of microwave energy to contents i n the vessel when a microwave transparent media used as a fluid coolant is present in the jacket. The instrument includes means for supplying a microwave transparent fluid coolant to the cooling jacket and means for venting the fluid coolant from the cooling jacket, a fluid coolant reservoir in communication with the cooling jacket, and a pump in communication with the reservoir and the cooling jacket for circulating flui d coolant from the fluid coolant reservoir through the cooling jacket and around the reaction vessel.