发明名称 |
COMPOSITIONS AND METHODS FOR DETERMINING AND PREDICTING TREATMENT RESPONSES FOR DEPRESSION AND ANXIETY |
摘要 |
The invention provides genetic means, including compositions (e.g., kits) and methods, to predict the efficacy of a treatment in depression and anxiety and to predict a patient's response to a particular a specific medication or treatment. The invention provides methods for diagnosing the presence of a psychiatric disorder or determining the outcome of a treatment for a psychiatric disorder. The invention provides methods for methods for diagnosing the presence of a psychiatric disorder in an individual by determining what corticotropin-releasing hormone receptor 1 (CRHR1) protein or transcript isoforms are expressed in an individual. The invention provides methods for diagnosing the presence of a psychiatric disorder in an individual by determining what protein or transcript isoforms are expressed in an individual wherein the protein is involved in the hypothalamic-pituitary-adrenal (HPA) axis pathway. |
申请公布号 |
CA2577141(A1) |
申请公布日期 |
2006.02.16 |
申请号 |
CA20052577141 |
申请日期 |
2005.08.12 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LICINIO, JULIO;IRIZARRY, KRISTOPHER J. L.;WONG, MA-LI;IRIZARRY, KATHERINE MISOURAS |
分类号 |
C07H21/04;C12P19/34;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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