发明名称 |
Production and use of novel peptide-based agents with bispecific antibodies |
摘要 |
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that specifically binds a targeted tissue and at least one other arm that specifically binds a targetable construct. The targetable construct comprises a carrier portion which comprises or bears at least one epitope recognizable by at least one arm of said bi-specific antibody or antibody fragment. The targetable construct further comprises one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bi-specific antibodies or antibody fragments, as well as methods for using them.
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申请公布号 |
US2006034759(A1) |
申请公布日期 |
2006.02.16 |
申请号 |
US20050198846 |
申请日期 |
2005.08.08 |
申请人 |
IMMUNOMEDICS, INC. |
发明人 |
GOLDENBERG DAVID M.;HANSEN HANS J.;LEUNG SHUI-ON;MCBRIDE WILLIAM J.;QU ZHENGXING |
分类号 |
A61K51/00;A61K47/48;A61K51/08;A61K51/10;A61P35/00;C07K7/06;C07K16/18;C07K16/30;C07K16/44;C07K16/46 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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