发明名称 |
COMPUESTOS DERIVADOS DE OXIMILO MACROCICLICO, INHIBIDORES DE PROTEASA DE HEPATITIS C; COMPOSICION FARMACEUTICA, UTIL PARA EL TRATAMIENTO DE INFECCION POR HEPATITIS C. |
摘要 |
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
申请公布号 |
CL2007001629(A1) |
申请公布日期 |
2008.02.08 |
申请号 |
CL20070001629 |
申请日期 |
2007.06.06 |
申请人 |
ENANTA PHARMACEUTICALS, INC. |
发明人 |
YING SUN, DEQIANG NIU, GUOYOU XU, YAT SUN OR, ZHEWANG. |
分类号 |
A61K38/06;A61P31/14;C07K5/08 |
主分类号 |
A61K38/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|