发明名称 Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
摘要 The invention relates to a substituted-pyrimidone derivative represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, R4, R5, n, p and q are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3beta, such as Alzheimer disease.
申请公布号 US2006035910(A1) 申请公布日期 2006.02.16
申请号 US20050224873 申请日期 2005.09.13
申请人 MITSUBISHI PHARMA CORPORATION 发明人 LOCHEAD ALISTAIR;SAADY MOURAD;SLOWINSKI FRANCK;YAICHE PHILIPPE
分类号 A61K31/519;C07D487/04 主分类号 A61K31/519
代理机构 代理人
主权项
地址