| 发明名称 |
COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS |
| 摘要 |
Novel acyl urea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory diseases, immunological diseases and cancer. |
| 申请公布号 |
WO2004101752(A3) |
申请公布日期 |
2006.02.16 |
| 申请号 |
WO2004US14394 |
申请日期 |
2004.05.07 |
| 申请人 |
THERACOS, INC.;NEOGI, PARTHA;DEY, DEBEDRANATH;FULLER, JOSEPH, C.;CHEN, LIANG;LI, TA-KAI |
发明人 |
NEOGI, PARTHA;DEY, DEBEDRANATH;FULLER, JOSEPH, C.;CHEN, LIANG;LI, TA-KAI |
| 分类号 |
A61P3/10;C07C235/34;C07C271/64;C07C275/50;C07C281/06;C07C317/22;C07D213/56;C07D213/64;C07D213/643;C07D213/75;C07D295/185;C12N |
主分类号 |
A61P3/10 |
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