发明名称 COMBINATIONS FOR TREATING IMMUNO-INFLAMMATORY DISORDERS
摘要 FIELD: medicine. ^ SUBSTANCE: the present deals with compositions, kits and their usage for manufacturing medicinal preparations for treating immuno-inflammatory disorders out of the group consisting of rheumatoid arthritis, psoriasis, ulcerous colitis, Crohn's disease, ankylosing spondylitis, multiple sclerosis (MS), type I diabetes, systemic lupus erythematosus, Sjogren's syndrome, fibromyalgia and insult-induced lethality of cerebral cells and, also, for suppressing the production of one or more pro-inflammatory cytokines. The compositions suggested contain the combination of two active ingredients: (i) dipyridamol and (ii) corticosteroid. Such a combination provides the suppression of immune inflammation due to decreasing pro-inflammatory cytokines, such as TNFalpha by hundreds times. ^ EFFECT: higher efficiency. ^ 54 cl, 4 ex, 3 tbl
申请公布号 RU2322984(C2) 申请公布日期 2008.04.27
申请号 RU20040113551 申请日期 2002.10.04
申请人 KOMBINATORKS, INKORPOREJTED 发明人 KEJT KERTIS;BORAJSI ALEKSIS;TSIMMERMANN GRANT;DZHOST-PRAJS EHDVARD ROJDON;MANIVASAKAM PALANIJANDI;KHERST NIKOL';FOULI MAJKL A.
分类号 A61K31/519;A61K;A61K31/56;A61K31/57;A61K31/573;A61K31/675;A61K45/06;A61P1/04;A61P3/10;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P25/00;A61P29/00;A61P37/00;A61P37/02;A61P43/00 主分类号 A61K31/519
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