IN VIVO DEGRADABLE/ABSORBABLE PRESSURE-SENSITIVE ADHESIVE MEDICAL MATERIAL COMPRISING ALBUMIN AND LOW-MOLECULAR BIODERIVATIVE

摘要

Conventional adhesives for biotissues have a drawback concerning either toxicity to the living body or adhesion strength. An in vivo degradable/absorbable pressure-sensitive adhesive medical material is provided which comprises an adhesive ingredient which is either of an organic solvent solution or aqueous solution of albumin and a water/organic solvent mixture solution of albumin and a curing ingredient which is a low-molecular derivative obtained from a di- or tricarboxylic acid present in the citric acid cycle by modifying the two or three carboxy groups with succinimidyl, sulfosuccinimidyl, maleimidyl, phthalimidyl, imidazolyl, nitrophenyl, or tresyl, which are electron-attracting groups, or with a derivative of any of these.