发明名称 |
Use of hmgb1 in the treatment of tissue damage and or to promote tissue repair |
摘要 |
It is described a composition comprising an effective amount of the HMGBl protein or functional parts thereof, of HMGBl expressing vectors, for the treatment of tissue damage and/or to promote tissue repair and regeneration. It is further described a composition comprising an effective amount of an antagonist of the HMGBl protein for the treatment of adverse effects induced by necrotic tissue, such as recruitment and activation of mveloid cells, loss of the barrier function of endothelia, edema.
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申请公布号 |
US2006035851(A1) |
申请公布日期 |
2006.02.16 |
申请号 |
US20050519427 |
申请日期 |
2005.05.31 |
申请人 |
BIANCHI MARCO E;PALUMBO ROBERTA;COLOGNESI CAPOGROSSI MAURIZIO;LIMANA FEDERICA;GERMANI ANTONIA |
发明人 |
BIANCHI MARCO E.;PALUMBO ROBERTA;COLOGNESI CAPOGROSSI MAURIZIO;LIMANA FEDERICA;GERMANI ANTONIA |
分类号 |
A61K48/00;C12N5/02;A61K38/00;A61K38/18;A61K39/395;A61K45/00;A61P9/10;A61P21/00;A61P29/00;A61P43/00;C07K14/47 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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