METHODS OF CREATING MODIFIED PROMOTERS RESULTING IN VARYING LEVELS OF GENE EXPRESSION
摘要
The present invention relates to a method of creating promoter cassettes that include modified precursor promoters and transforming a population of bacterial host cells with a promoter library comprising the promoter cassettes resulting in bacterial clones having a range of expression levels of a gene of interest. The invention further relates to selecting a transformed bacterial host cell which has an optimum level of gene expression.
申请公布号
WO03089604(A3)
申请公布日期
2006.02.16
申请号
WO2003US12044
申请日期
2003.04.18
申请人
GENENCOR INTERNATIONAL, INC.;CERVIN, MARGUERITE, A.;VALLE, FERNANDO