发明名称 |
SUBSTITUTED PYRIMIDINE DERIVATIVES |
摘要 |
<p>This invention relates to compounds of Formula I, a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, or a pharmaceutically acceptable salt of a prodrug thereof. The compounds interact with CRF<SUB>1 </SUB>receptors, including human CRF<SUB>1 </SUB>receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety-related disorders such as anxiety, and mood disorders such as major depression.</p> |
申请公布号 |
EP1625115(A1) |
申请公布日期 |
2006.02.15 |
申请号 |
EP20040729473 |
申请日期 |
2004.04.26 |
申请人 |
PHARMACIA & UPJOHN COMPANY LLC |
发明人 |
CORBETT, JEFFREY, WAYNE;ENNIS, MICHAEL, DALTON;FRANK, KRISTINE, ELISABETH;FU, JIAN-MIN;HOFFMAN, ROBERT, LOUIS;VERHOEST, PATRICK |
分类号 |
C07D213/72;C07D239/42;(IPC1-7):C07D213/72 |
主分类号 |
C07D213/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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