发明名称 A METHOD FOR THE PREPARATION OF PHENYL-M-TOLYLPHOSPHATE SALT OF DI(2-CHLOROETHYL) AMINE
摘要 A method for the preparation of phenyl-m-tolylphosphate salt of di(2-chloroethyl) amine comprises the reaction of phenyl-m-tolylphosphoric acid with di(2- chloroethyl) amine. A synthesis is performed in one stage without isolation of intermediate substances in the interaction of hydrochloric salt ofdi(2- chloroethyl) amine, chloroanhydride phenyl-m- tolylphosphoric acid and triethylamine in the aqueous medium. The crystalline product is isolated of reaction mixture by filtration and cleaning.
申请公布号 UA12338(U) 申请公布日期 2006.02.15
申请号 UA20050001156 申请日期 2005.02.09
申请人 SCIENTIFIC-AND-PRACTICAL CENTER OF ENDOVASCULAR NEURORADIOSURGERY OF AMSU 发明人 SCHEHLOV VIKTOR IVANOVYCH;KUZMENKO IVAN YOSYPOVYCH;SCHEHLOV DMYTRO VIKTOROVYCH
分类号 A61K31/131;A61K31/661;A61P35/00;C07C211/03;C07F9/12;(IPC1-7):A61K/131;A61K/661;A61P/00;C07C/03;C07F/12 主分类号 A61K31/131
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