| 发明名称 |
APOPTOSIS INDUCER FOR CANCER CELL |
| 摘要 |
<p>The present invention revealed that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells and their proliferation is suppressed. Compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are thought to have the activity of inducing apoptosis.</p> |
| 申请公布号 |
EP1625853(A1) |
申请公布日期 |
2006.02.15 |
| 申请号 |
EP20040733937 |
申请日期 |
2004.05.19 |
| 申请人 |
GENECARE RESEARCH INSTITUTE CO., LTD |
发明人 |
TAKAGI, MOTOKI;SHIMAMOTO, AKIRA;FURUICHI, YASUHIRO;SATO, AYUMI |
| 分类号 |
A61K38/52;A61K31/713;C12N15/113;G01N33/50;(IPC1-7):A61K45/00;C12Q1/02;A61K38/00;C12Q1/68;C12Q1/25;C12N15/11;A61K39/395 |
主分类号 |
A61K38/52 |
| 代理机构 |
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