Conjugates of defined stoichiometry

摘要

The invention relates to a conjugate consisting of a polypeptide having between 50 and 5000 amino acids and a hydrophilic linker molecule said linker having a molecular weight between 1 and 15 kD and between 4 and 60 charged residues, characterized in that said conjugate comprises at least one polypeptide-linker product of uniform stoichiometry in a pre-selected amount.