摘要 |
FIELD: biochemistry, in particular preparation of chloro-substituted nitrophenol. ^ SUBSTANCE: claimed method includes oxidative chlorination of 4-nitrophenol with mixture of hydrochloric acid and 19-33 % hydrogen peroxide in 30-60 % sulfuric acid medium. Molar ratio of 4-nitrophenol/oxiding agent is 1:1. Obtained product precipitate is filtered and washed with cold water. Preparations of present invention are useful as active ingredient for antifungal drugs in skin lesions. ^ EFFECT: improved method; increased yield of target product. ^ 1 ex |