发明名称 |
Treatment of viral encephalitis by agents blocking alpha-VLA-4 integrin function |
摘要 |
The invention provides methods of treating viral encephalitis in a patient. Such methods entail administering to the patient an effect amount of an agent that inhibits binding of leukocytes to brain endothelial cells via leukocyte surface antigen alpha-4 integrin. Such agents include antibodies and small molecules that specially bind to alpha-4 integrin.
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申请公布号 |
US2006029600(A1) |
申请公布日期 |
2006.02.09 |
申请号 |
US20040016386 |
申请日期 |
2004.12.16 |
申请人 |
ATHENA NEUROSCIENCES JOHNS HOPKINS UNIVERSITY |
发明人 |
RUBIN STEVEN A.;YEDNOCK THEODORE A.;CARBONE KATHRYN M. |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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