| 发明名称 |
IMMUNOGLOBULINS COMPRISING PREDOMINANTLY A GAL2GLCNAC2MAN3GLCNAC2 GLYCOFORM |
| 摘要 |
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is Gal<SUB>2</SUB>GlcNAc<SUB>2</SUB>Man<SUB>3</SUB>GlcNAc<SUB>2</SUB> lacking fucose. |
| 申请公布号 |
WO2006014683(A2) |
申请公布日期 |
2006.02.09 |
| 申请号 |
WO2005US25656 |
申请日期 |
2005.07.19 |
| 申请人 |
GLYCOFI, INC.;GERNGROSS, TILLMAN U.;LI, HUIJUAN;WILDT, STEFAN |
发明人 |
GERNGROSS, TILLMAN U.;LI, HUIJUAN;WILDT, STEFAN |
| 分类号 |
C07K16/22;A61K39/395;C07K16/24;C07K16/28;C12N15/09;C12N15/10 |
主分类号 |
C07K16/22 |
| 代理机构 |
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