发明名称 |
METHOD OF PRODUCING GLYCOPROTEIN COMPOSITION |
摘要 |
It is intended to provide a cell having an RNA, which inhibits the function of an enzyme catalyzing the reaction of converting GDP-mannose into GDP-4-keto,6-deoxy-GDP mannose, transferred thereinto; a method of producing a glycoprotein composition by using this cell; a cell having an RNA which inhibits the function of an enzyme participating in the sugar chain modification of the binding, via a-bond, of the 1-position of fucose to the 6-position of N-acetylglucosamine at the reducing end of an N-glycoside bond type complex sugar chain, an RNA which inhibits the function of an enzyme protein participating in the intracellular synthesis of a sugar nucleotide GDP-fucose, or an RNA inhibiting the function of a protein participating in the intracellular transport of a sugar nucleotide GDP-fucose into the Golgi body, transferred thereinto; a method of producing a glycoprotein composition by using this cell; and so on. |
申请公布号 |
WO2006013964(A1) |
申请公布日期 |
2006.02.09 |
申请号 |
WO2005JP14408 |
申请日期 |
2005.08.05 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD.;NISHIYA, HARUE;SATOH, MITSUO;MORI, KATSUHIRO |
发明人 |
NISHIYA, HARUE;SATOH, MITSUO;MORI, KATSUHIRO |
分类号 |
(IPC1-7):C12N15/11;C12P21/08;C12P21/02;C12N5/10;C07K2/00;C07K16/00;A61K39/395 |
主分类号 |
(IPC1-7):C12N15/11 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|