发明名称 COMBINATION COMPRISING A BCRP INHIBITOR AND 4-(4-METHYLPIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL)PYRIMIDIN-2-YLAMINO)PHENYL]-BENZAMIDE
摘要 The present invention relates to a combination which comprises a BCRP inhibitor and Compound I of formula (I), in which the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, especially in the delay of progression or treatment of cancer, and to pharmaceutical compositions comprising such combinations.
申请公布号 WO2006012958(A2) 申请公布日期 2006.02.09
申请号 WO2005EP07090 申请日期 2005.06.30
申请人 THE NETHERLANDS CANCER INSTITUTE;BREEDVELD, PAULINE;CIPRIANI, GRETA;PLUIM, DICK;SCHELLENS, JOHANNES, HENRICUS, MATTHIAS;VAN TELLINGEN, OLAF;WIELINGA, PIETER, ROELAND 发明人 BREEDVELD, PAULINE;CIPRIANI, GRETA;PLUIM, DICK;SCHELLENS, JOHANNES, HENRICUS, MATTHIAS;VAN TELLINGEN, OLAF;WIELINGA, PIETER, ROELAND
分类号 A61K45/06;A61K31/506;A61P35/00 主分类号 A61K45/06
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