ARYLPYRROLIDINE DERIVATIVES AS NK-1/SSRI ANTAGONISTS
摘要
<p>The present disclosure relates to chemical compounds and their use in treatment of human diseases. A particular embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salts or solvates thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.</p>
申请公布号
WO2006014665(A2)
申请公布日期
2006.02.09
申请号
WO2005US25631
申请日期
2005.07.20
申请人
BRISTOL-MYERS SQUIBB COMPANY;WU, YONG-JIN;HE, HUAN;BRONSON, JOANNE, J.