发明名称 METHODS FOR PREPARING METAL-CARBORANE COMPLEXES FOR RADIOIMAGING AND RADIOTHERAPY
摘要 The present invention relates to a method of preparing metal-carborane complexes comprising reacting a salt of the formula: [M(CO)3(X m)3](1 + 3m), wherein M is selected from a radioisotope of rhenium (Re), technetium (Tc) and any other radioisotope binding in the same fashion, X is the same of different and is, independently, any suitable ligand and m is the formal charge for ligand X, with a nido-dicarbollide dianion in the presence of a hard bas e. In an embodiment of the invention, the hard base is a source of fluorid e.
申请公布号 CA2477020(A1) 申请公布日期 2006.02.09
申请号 CA20042477020 申请日期 2004.08.09
申请人 MCMASTER UNIVERSITY 发明人 VALLIANT, JOHN F.;SOGBEIN, OYEBOLA O.
分类号 C07F15/00;A61K51/00;C07F13/00 主分类号 C07F15/00
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