发明名称 |
MSIA-SRM ASSAY FOR BIOMARKER ANALYSIS |
摘要 |
The present disclosure provides assays, methods and signature peptides for the identification and quantification of biomarkers in a sample. In particular, the present disclosure relates to the development of mass spectrometric immunoassays with selected reaction monitoring mass spectrometry (MSIA-SRM MS) platforms for biomarker analysis. The MSIA-SRM MS platform may specifically be used for discriminating between particular variants of one or more biomarkers. In addition, the MSIA-SRM platform of the present invention may identify and/or quantify a biomarker and/or its variants present at low abundance in a sample. |
申请公布号 |
US2016209412(A1) |
申请公布日期 |
2016.07.21 |
申请号 |
US201414913476 |
申请日期 |
2014.08.20 |
申请人 |
NUCLEA BIOTECHNOLOGIES, INC. |
发明人 |
Tam Sun W.;Xu Ying;Zhang Yunhui;Drescher Christopher S.;Muraca Patrick J |
分类号 |
G01N33/573;H01J49/00;C07K7/08;C07K14/00;C07K7/06 |
主分类号 |
G01N33/573 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Pittsfield MA US |