AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY
摘要
The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.
申请公布号
KR20060013377(A)
申请公布日期
2006.02.09
申请号
KR20057020313
申请日期
2005.10.25
申请人
SAMYANG CORPORATION
发明人
SEO, MIN HYO;KIM, BONG OH;CHOI, IN JA;SHIM, MYUNG SEOB;LEE, SA WON;HYUN, MYUNG HAN;YU, JUNG IL;CHANG, DONG HOON;KIM, JEONG KYUNG;YOON, HYE JEONG