DRUG CANDIDATE SELECTION BY HYDROGEN EXCHANGE CHARACTERIZATION OF LIGAND-INDUCED RECEPTOR CONFORMATION
摘要
<p>A method is provided of selecting a compound that (a) binds a receptor, and (b) on binding the receptor, induces a perturbation in the conformation of the receptor, which conformational perturbation is correlated with a particular pharmacological activity.</p>
申请公布号
WO2006014160(A2)
申请公布日期
2006.02.09
申请号
WO2004US21472
申请日期
2004.07.02
申请人
EXSAR CORPORATION;SOUTHERN, MARK, ROBERT;HAMURO, YOSHITOMO;GRIFFIN, PATRICK, ROBERT
发明人
SOUTHERN, MARK, ROBERT;HAMURO, YOSHITOMO;GRIFFIN, PATRICK, ROBERT
