发明名称 ARTIFICIAL OXYGEN CARRIER CONTAINING METHEMGLOBIN FORMATION INHIBITOR
摘要 <P>PROBLEM TO BE SOLVED: To provide a methemglobin formation inhibitor containing L-tyrosine, to provide an artificial oxygen carrier containing the methemglobin formation inhibitor, and to provide, concretely, an artificial oxygen carrier preparation capable of preventing increase in a methemoglobin content caused by oxidation of hemoglobin, etc., enclosed in a lipid endoplasmic reticulum having a bilayer membrane structure and suitable for storage for a long period. <P>SOLUTION: The methemglobin formation inhibitor containing the L-tyrosine and the endoplasmic reticulum containing the methemglobin formation inhibitor are provided, respectively. The oxygen transfusion preparation which prevents the increase in the methemoglobin content caused by the oxidation of hemoglobin, etc., enclosed in the lipid endoplasmic reticulum having the bilayer membrane structure and is suitable for the storage for the long period is concretely provided. <P>COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006036748(A) 申请公布日期 2006.02.09
申请号 JP20040309268 申请日期 2004.10.25
申请人 OXYGENIX:KK;UNIV WASEDA 发明人 TAKEOKA SHINJI;TSUCHIDA HIDETOSHI;SAKAI HIROMI;TERAMURA YUJI;AHEI TOMOYASU
分类号 A61K47/18;A61K9/127;A61K47/34 主分类号 A61K47/18
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