发明名称 SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA N-
摘要 The present invention concerns a compound of general formula (I): in which n=0 or 1, R1 represents an optionally substituted alkyl chain, in particular substituted alkyl chain, in particular substituted with fluorine, X is chosen from N and CH, and R2 is chosen from optionally substituted phenyl and benzyl, wherein the heterocycles having 6 vertices comprise one, two or three nitrogen atoms. The present invention also concerns the use of this compound as a medicament, in particular in the treatment of bacterial and mycobacterial infections such as tuberculosis in combination with an antibiotic that is active against bacteria and/or mycobacteria, said compound potentiating the activity of said antibiotic.
申请公布号 HK1215254(A1) 申请公布日期 2016.08.19
申请号 HK20160103219 申请日期 2016.03.18
申请人 UNIVERSITE DE DROIT ET DE LA SANTE LILLE 2 发明人 Nicolas WILLAND N;Benoit DEPREZ B;Alain BAULARD A;Priscille BRODIN P;Marion FLIPO M;Lucie MAINGOT L
分类号 C07D;A61K;A61P 主分类号 C07D
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