发明名称 PROCESS FOR PROTEIN EXTRACTION
摘要 The invention includes a process for extracting a target protein from E.coli cells that includes lowering the pH of a whole E . coli cell solution to form an acidic solution, disrupting the cells to release the protein into the acidic solution, and separating the cellular debris from the released protein to obtain a protein product enriched in the heterologous target protein. The invention also includes addition of a solubility enhancer.
申请公布号 EP1539798(A4) 申请公布日期 2006.02.08
申请号 EP20030752068 申请日期 2003.09.05
申请人 GENENTECH, INC. 发明人 GEHANT, RICHARD, L.
分类号 C07K1/36;C07K14/245 主分类号 C07K1/36
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