METHODS FOR MEASURING THE INSULIN RECEPTOR ALPHA SUBUNIT

摘要

Presence of free insulin receptor ±-subunit in blood was discovered. Furthermore, methods for measuring the insulin receptor ±-subunit was provided, the method comprising the steps of contacting the insulin receptor ±-subunit in a blood sample with an antibody recognizing the insulin receptor ±-subunit, and detecting the binding between the two. Measurement of the free insulin receptor ±-subunit in the blood is useful for evaluating risk factors for diabetes. In addition, the measurement methods of the present invention showed that concentrations of the free insulin receptor ±-subunit in the blood of diabetes or cancer patients are significantly high. Free insulin receptor ±-subunit in blood is useful as a marker for diabetes or cancer.