发明名称 |
METHOD OF TREATING SJÖGREN'S SYNDROME |
摘要 |
A method of treating Sjögren's syndrome in a patient eligible for treatment is provided involving administering an effective amount of an antagonist that binds to a B-cell surface marker to the patient to provide significant improvement over baseline in two or more of dryness, fatigue, and joint pain on a Visual Analogue Scale, and an article of manufacture therefor. Methods and articles are also provided involving treating Sjögren's syndrome in a subject eligible for treatment is provided involving administering an effective amount of an antibody that binds to a B-cell surface marker to the subject to provide an initial exposure and a subsequent exposure to the antibody within certain dosing regimens and an article of manufacture therefor. |
申请公布号 |
WO2006012508(A2) |
申请公布日期 |
2006.02.02 |
申请号 |
WO2005US26027 |
申请日期 |
2005.07.21 |
申请人 |
GENENTECH, INC.;HITRAYA, ELENA |
发明人 |
HITRAYA, ELENA |
分类号 |
A61P37/00;A61K39/395;C07K16/28 |
主分类号 |
A61P37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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