| 摘要 |
A retroviral packing cell (I), comprising the retroviral genes gag, pol and glycoproteins GP-1 and GP-2 of the LCMV coding gene gp, or a part of these, is new. Independent claims are also included for the following: (1) preparation of (I); (2) a retroviral packing cell (II) expressing pseudo-type virions, which contain LCMV glycoproteins in their coat; (3) pseudo-type virions (III) produced by (II); (4) a retroviral pseudo-type vector (IV), produced by cultivating (I); (5) preparation of (IV); (6) a lymphocyte Choriomeningitis virus (V), comprising the gene gp, which encodes the 498 amino acid sequence, fully defined in the specification, or a part of it; (7) a protein (VI) having the fully defined 498 amino acid sequence, or a part of it; and (8) a nucleic acid sequence (VII) having the fully defined 1497 base pair sequence, or a part of it. |
