发明名称 PROCESS FOR THE PREPARATION OF RACEMIC 2-[[2-(4-HYDROXYPHENYL)ETHYL]THIO]-3-[4-(2-[4-[(METHYLSULFONYL)OXY]PHENOXY]ETHYL)PHENYL]-PROPANOIC ACID
摘要 The present invention provides a process for the preparation of substantially racemic 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4- [(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]-propanoic acid which comprises reacting 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl) oxy]phenoxy}ethyl)phenyl]propanoic acid enriched in one enantiomer with a base in an inert solvent.
申请公布号 KR20060010840(A) 申请公布日期 2006.02.02
申请号 KR20057024130 申请日期 2005.12.16
申请人 ASTRAZENECA AB 发明人 ANDERSSON KJELL;LINDSTEDT ALSTERMARK EVA LOTTE;SORENSEN HENRIK
分类号 C07C319/20;A61K31/192;C07C323/56;C07F7/18 主分类号 C07C319/20
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