发明名称 THERAPEUTIC USE OF ANTI-TF-ANTIGEN ANTIBODY
摘要 The invention is related to administration of monoclonal antibody JAA-Fl 1 to an individual for inhibition of metastasis and/or inhibition of growth of cells which express TF­Ag, or for detection of tumors or metastatic foci which express TF-Ag. For inhibition of metastasis or inhibition of growth of cells expressing TF-Ag, the method comprises administering to the individual a therapeutic amount of mAb JAA-F11, wherein the JAA-F11 mAb inhibits the metastasis and/or growth of the TF-Ag expressing cancer cells. For detection of tumors or metastatic foci, mAb JAA-F11 is conjugated to a detectable label and administered to the individual. Detection of the label identifies metatstatic foci or tumors which comprise cancer cells expressing TF-Ag.
申请公布号 WO2006012616(A2) 申请公布日期 2006.02.02
申请号 WO2005US26317 申请日期 2005.07.26
申请人 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK AT BUFFALO STOR INTELLECTUAL PROPERTY DIVISION;RITTENHOUSE-OLSON, KATE 发明人 RITTENHOUSE-OLSON, KATE
分类号 A61K39/395;A61K36/47;A61K51/00 主分类号 A61K39/395
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