Provided herein are targetable constructs that are multivalent carriers of bi-specific antibodies, i.e., each molecule of a targetable construct can serve as a carrier of two or more bi-specific antibodies. Also provided are targetable complexes formed by the association of a targetable construct with two or more bi-specific antibodies. The targetable constructs and targetable complexes of the invention are incorporated into biosensors, kits and pharmaceutical compositions, and are used in a variety of therapeutic and other methods.
申请公布号
WO2005004809(A3)
申请公布日期
2006.02.02
申请号
WO2004US20995
申请日期
2004.07.01
申请人
IMMUNOMEDICS, INC.;HANSEN, HANS, J.;MCBRIDE, WILLIAM, J.;QU, ZHENGXING
发明人
HANSEN, HANS, J.;MCBRIDE, WILLIAM, J.;QU, ZHENGXING