发明名称 Methods and compositions for reducing toxicity associated with leflunomide treatment
摘要 The invention relates to methods and compositions useful in alleviating or reducing toxicity associated with leflunomide administration without reducing its bioactivity, e.g., without reducing its immunosuppressive activity, that is, utilizing a bioavailable pyrimidine compound to ameloriate the toxic effects caused by leflunomide compounds.
申请公布号 US2006024376(A1) 申请公布日期 2006.02.02
申请号 US20040903681 申请日期 2004.07.30
申请人 THE UNIVERSITY OF CHICAGO 发明人 WILLIAMS JAMES W.
分类号 A61K31/513;A61K9/14;A61K31/505 主分类号 A61K31/513
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