Latent fluorescent compounds, comprising a fluorescent molecule with one or more blocking groups attached and optionally one or more urea-containing groups are provided. The urea-containing group can be used to further attach one or more molecules of interest, such as proteins, peptides or nucleic acids. The blocking group(s) is released from the latent fluorescent compound by reaction with a trigger, forming the fluorescent molecule which can be detected. Also provided herein are methods of using latent fluorescent compounds to detect triggers.
申请公布号
WO2005047245(A3)
申请公布日期
2006.02.02
申请号
WO2004US38183
申请日期
2004.11.15
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;THE PENN STATE RESEARCH FOUNDATION;RAINES, RONALD, T.;CHANDRAN, SUNIL, S.;GLASS, TIMOTHY, E.;LAVIS, LUKE, D.
发明人
RAINES, RONALD, T.;CHANDRAN, SUNIL, S.;GLASS, TIMOTHY, E.;LAVIS, LUKE, D.