Substituted piperazines

摘要

The invention comprises compounds of the formula in which X represents a negative atom or group of atoms, e.g. Br, Cl, NO2 or HSO3, and a process for their preparation comprising reacting piperazine, or an acid addition salt thereof, with a functional derivative of an appropriately substituted furfurylidene acetic acid, e.g. the anhydride or a halide or ester. Pharmaceutical compositions, having anti-depressive, analgesic, anti-pyretic and anti-inflammatory activity, for oral or parenteral administration, comprise a compound of the invention together with a pharmaceutical carrier.