发明名称 |
IMMEDIATELY DISINTEGRABLE MEDICINAL COMPOSITIONS |
摘要 |
The present invention relates to a pharmaceutical composition useful for rapid disintegration, which comprises a sparingly soluble medicament held on a gel-forming water-soluble polymer as a solid dispersion, wherein it contains a salt substance that comprises an alkali and a weak or strong acid and has an endothermic standard enthalpy of solution or heat of solution. Since rapid disintegration of the pharmaceutical composition of the present invention and rapid dissolution of the medicament contained in the preparation can be made in the digestive tracts pH-independently, good bioavailability can be attained. |
申请公布号 |
EP1008354(A4) |
申请公布日期 |
2006.02.01 |
申请号 |
EP19970950375 |
申请日期 |
1997.12.24 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
TAKAGI, HIROKAZU;KAJIYAMA, ATSUSHI;YANAGISAWA, MASAHIRO |
分类号 |
A61K9/16;A61K9/20 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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