发明名称 |
Enzymatic reductions with dihydrogen via metal catalyzed cofactor regeneration |
摘要 |
The invention provides a process for reducing an unsaturated organic compound, comprising mixing the unsaturated organic compound and H 2 in the presence of a catalyst to form a reduced organic product, wherein the catalyst comprises: a) at least one metal salt or complex, b) at least one nicotinamide cofactor; and c) a nicotinamide cofactor dependent enzyme, wherein: i) when the metal salt or complex is a platinum carbonyl cluster complex, the catalyst does not comprise a redox active dye; and ii) when the metal salt or complex is a rhodium phosphine complex, the nicotinamide cofactor dependent enzyme is not a mixture of horse liver alcohol dehydrogenase and lactate dehydrogenase. |
申请公布号 |
EP1621613(A1) |
申请公布日期 |
2006.02.01 |
申请号 |
EP20050021016 |
申请日期 |
2000.03.10 |
申请人 |
EASTMAN CHEMICAL COMPANY |
发明人 |
HEMBRE, ROBERT T.;WAGENKNECHT, PAUL S.;PENNEY, JONATHAN M. |
分类号 |
C12N9/02;C12P1/00;C12P7/00;C12P7/02;C12P13/02;C12P19/36;C12P21/00 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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